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Total 11675 results found since Jan 2013.
Exosomal STAT1 derived from high phosphorus ‑stimulated vascular endothelial cells induces vascular smooth muscle cell calcification via the Wnt/β‑catenin signaling pathway
In conclusion, the present results indicated that exosomal STAT1 derived from HP‑treated HUVECs could promote VSMC calcification, and activation of the Wnt/β‑catenin pathway may be a potential mechanism of the VSMC calcification promoted by exosomes.PMID:36281932 | DOI:10.3892/ijmm.2022.5195
Source: International Journal of Molecular Medicine - October 25, 2022 Category: Molecular Biology Authors: Zheng Qin Yupei Li Jiameng Li Luojia Jiang Zhuyun Zhang Kaixi Chang Qinbo Yang Shanshan Chen Ruoxi Liao Baihai Su Source Type: research
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling.
Abstract
Blood vessel stability is essential for embryonic development; in the adult, many diseases are associated with loss of vascular integrity. The ETS transcription factor ERG drives expression of VE-cadherin and controls junctional integrity. We show that constitutive endothelial deletion of ERG (Erg(cEC-KO)) in mice causes embryonic lethality with vascular defects. Inducible endothelial deletion of ERG (Erg(iEC-KO)) results in defective physiological and pathological angiogenesis in the postnatal retina and tumors, with decreased vascular stability. ERG controls the Wnt/β-catenin pathway by promoting β-c...
Source: Developmental Cell - January 12, 2015 Category: Cytology Authors: Birdsey GM, Shah AV, Dufton N, Reynolds LE, Osuna Almagro L, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Göttgens B, Hodivala-Dilke K, Gerhardt H, Adams RH, Randi AM Tags: Dev Cell Source Type: research
A search map for organic additives and solvents applicable in high-voltage rechargeable batteries
Phys. Chem. Chem. Phys., 2016, Advance Article DOI: 10.1039/C6CP05800K, PaperMin Sik Park, Insun Park, Yoon-Sok Kang, Dongmin Im, Seok-Gwang Doo A search map composed of the redox potentials of [similar]1 000 000 organic compounds is theoretically generated for finding novel electrolytes. The quantitative relationship between the redox potentials and functional groups is suggested. The cycle performance of lithium ion batteries is improved by applying a screened anodic additive. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 19, 2016 Category: Chemistry Authors: Min Sik Park Source Type: research
Fast material search of lithium ion conducting oxides using a recommender system
J. Mater. Chem. A, 2020, Advance Article DOI: 10.1039/D0TA02556A, PaperKota Suzuki, Kosei Ohura, Atsuto Seko, Yudai Iwamizu, Guowei Zhao, Masaaki Hirayama, Isao Tanaka, Ryoji Kanno Fast material search using a recommender system is demonstrated to obtain novel lithium ion conducting oxides. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - June 5, 2020 Category: Chemistry Authors: Kota Suzuki Source Type: research
Bipolar Disorder and Manic-like Symptoms in Alzheimer's, Vascular and Frontotemporal Dementia: A Systematic Review
CONCLUSION: Prevalence, clinical features and treatment response to pharmacotherapy of manic syndromes in patients with dementia may be differentially affected by the nature of the underlying neurodegenerative conditions.PMID:35794767 | DOI:10.2174/1570159X20666220706110157
Source: Current Neuropharmacology - July 7, 2022 Category: Drugs & Pharmacology Authors: Camilla Elefante Giulio Emilio Brancati Samuele Torrigiani Salvatore Amadori Sara Ricciardulli Gabriele Pistolesi Lorenzo Lattanzi Giulio Perugi Source Type: research
Sensors, Vol. 23, Pages 5465: Li2100deplMoO4 Scintillating Bolometers for Rare-Event Search Experiments
We report on the development of scintillating bolometers based on lithium molybdate crystals that contain molybdenum that has depleted into the double-β active isotope 100Mo (Li2100deplMoO4). We used two Li2100deplMoO4 cubic samples, each of which consisted of 45-millimeter sides and had a mass of 0.28 kg; these samples were produced following the purification and crystallization protocols developed for double-β search experiments with 100Mo-enriched Li2MoO4 crystals. Bolometric Ge detectors were utilized to register the scintillation photons that were emitted by the Li2100deplMoO4 crystal scintil...
Source: Sensors - June 9, 2023 Category: Biotechnology Authors: Iulian C. Bandac Alexander S. Barabash Laurent Berg é Yury A. Borovlev Jos é Maria Calvo-Mozota Paolo Carniti Maurice Chapellier Ioan Dafinei Fedor A. Danevich Louis Dumoulin Federico Ferri Andrea Giuliani Claudio Gotti Philippe Gras Veronika D. Grigori Tags: Article Source Type: research
Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signaling.
Abstract
Vascular endothelial growth factor receptor-2 (VEGFR-2), which is a key determinant of the angiogenecic response, is decreased in diabetic mice under oxidative stress. β-transduction repeat-containing protein (β-TrCP) has been reported to participate in VEGFR-2 degradation in thyroid cancer cells. Additionally, glycogen synthase kinase-3β (GSK‑3β) acts as a mediator in the β-TrCP-induced degradation of several proteins. However, the role played by β-TrCP and GSK‑3β in the degradation of VEGFR-2 in endothelial cells where hyperglycemia had been induced was not fully understood. In the present ...
Source: International Journal of Molecular Medicine - February 18, 2016 Category: Molecular Biology Authors: Wu W, Zhang D, Pan D, Zuo G, Ren X, Chen S Tags: Int J Mol Med Source Type: research
